Norfolk and Suffolk NHS Foundation Trust
Pharmacy, Hellesdon Hospital, Norwich, NR6 5BE
http://www.nsft.nhs.uk/

Professor Stephen Bazire
01603-421452
steve.bazire@nsft.nhs.uk

What sort of side-effects might occur if I am taking carbamazepine?

The table below will show you some of the main side effects you might get from carbamazepine.

Side effect

What happens

What to do about it

COMMON (more than about 1 in 10 people might get these)

Sleepiness

Feeling sleepy, drowsy or sluggish. It can last for a few hours after taking your dose.

Don't drive or use machinery. Ask your doctor if you can take your carbamazepine at a different time of the day or have the sustained release (Retard) tablet.

Diplopia

Seeing double or "double vision".

Don't drive or use machinery. See your doctor if you are worried. Sustained release tablets (Retard) may help.

Dizziness

Feeling light-headed and faint.

Don't stand up too quickly.
Try and lie down when you feel it coming on. Don't drive.

Stomach upset

Feeling sick and being sick. You may have a dry mouth.

If it is bad, contact your doctor. It may be possible to adjust your dose or when you take the carbamazepine.

UNCOMMON (less than about 1 in 10 people might get these)

Headache

When your head is painful and pounding.

Try paracetamol. Your pharmacist will be able to advise if this is safe to take with any other medicines you may be taking.

Ataxia

Being very unsteady on your feet.

Your carbamazepine level may be too high. Contact your doctor now. A blood test may be needed.

RARE (less than about 1 in 100 people might get these)

Constipation

When you want to poop but can't (the opposite of diarrhoea). You can't pass a motion

Make sure you eat enough fibre, cereal or fruit. Make sure you are drinking enough fluid. Make sure you keep active and get some exercise e.g. walking. If this does not help, ask your doctor or pharmacist for a mild laxative.

Confusion

Your mind is all mixed up.

Your carbamazepine level may be too high. Contact your doctor now. A blood test may be needed.

Erythematous rash

A red rash seen anywhere on the skin.

Stop taking carbamazepine and contact your doctor now.

Ankle oedema

Swelling on the ankles, legs or feet

It is not usually dangerous. Tell your doctor next time you meet.

SIADH (syndrome of inappropriate antidiuretic hormone hypersecretion)

Symptoms include not passing much urine, headache, confusion, tiredness and, if very severe, seizures and coma.

This can be dangerous. Contact your doctor now.
SIADH can lead to hyponatraemia (low sodium), and water intoxication

RARE (less than about 1 in 1000 people might get these)

Agranulocytosis or thrombocytopenia

You may get more infections, bruise more easily or have a sore throat or a temperature.

See your doctor now if you get an infection, sore throat, fever or bruise more easily. You may need a blood test.

Do not be worried by this list of side effects. Some people get no side effects at all and others may get some effects that are not listed in this table. Side effects tend to be worse with higher doses. Starting with a lower dose sometimes helps. If you think you might have a side effect to your medicine, you should discuss this with your doctor, nurse of pharmacist. You should also see the manufacturer's information leaflet.

Updated 12.11

Main pharmacy contact points

Main Trust switchboard in Norwich, tel: 01603-421421
Dispensary and all enquiries, tel: 01603-421212, fax: 01603-421365
Pharmacy office tel: 01603-421319
Medicines Information tel: 01603-421212
Unthank Road pharmacy tel: 01603-750031
Deputy Director and Clinical Pharmacy Manager John Hunter, tel: 01603-421364

Opening hours:
Main pharmacy open Monday to Friday: 8.30-16.30 (open at 9.15 on Wednesdays for staff meeting)
Unthank Road pharmacy tel: 01603-671917 open 9.15-12.00 Monday to Friday, also Tuesday and Wednesday afternoons for dose assessments.

Service objectives:
The pharmacy service to Norfolk and Suffolk NHS Foundation Trust has five main aims:

  1. Efficient drug distribution and purchasing
  2. Provision of accurate and independent education and information about medicine therapy to service users and carers
  3. Information and education for Trust and other professionals, and voluntary helpers
  4. Clinical activities to help ensure the optimum use of drug therapies
  5. Medicine management to ensure the most cost-effective use is made of resources